Interpreting Gonadal Hormones

Low FSH LH  Raised Testosterone

Over-replacement of testosterone

Exogenous Testosterone

Testicular tumour

Adrenal Tumour

Normal FSH LH levels Raised Testosterone

Raised SHBG levels in liver disease

Constitutional raised Testosterone

Genetic raised SHBG

 

Raised FSH LH and Raised Testosterone

Complete or partial Androgen insensitivity

Exogenous GNHRH Therapy

 

 

Low FSH LH  Normal Testosterone 

  1. Normal

 

Normal FSH LH normal testosterone

 

Normal

Raised FSH LH  Normal Testosterone

  1. Testicular Failure
  2. Testicular injury
  3. Klinefelters syndrome

 

 

Low FSH LH Low Testosterone 

  1. Pituitary failure
  2. Recovering from major illness
  3. Anorexia nervosa
  4. Pre pubertal

 

Normal FSH LH  Low Testosterone

  1. Metabolic syndrome
  2. hypopituitarism
  3. Obesity
  4. Type 2 diabetes Mellitus

 

Raised FSH LH  Low Testosterone 

  1. Testicular failure
  2. Klinefelters syndrome